Early in production on The Bride in 1984, Clancy Brown's transformation into Frankenstein's monster became a genuine medical ordeal. The prosthetic makeup took nearly four hours to apply each day, but the production's European adhesive contained a dangerous chemical problem: unlike the surgical-grade Duo adhesive normally used for latex prosthetics, it lacked an additive that neutralized the ammonia used to liquefy raw latex. As Brown later explained, the latex itself was tolerable, but the ammonia effectively ate away at the skin beneath the makeup. His face became so irritated that filming had to stop for approximately two weeks while he recovered. Afterward, makeup artist Sarah Monzani replaced the original adhesive with a contact cement Brown could tolerate, allowing the production to resume. The incident was not a supernatural curse, but it was precisely the kind of punishing practical-effects failure that could derail a period production and leave its lead actor physically damaged.
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